Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | MC1R | Q01726 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576148 | 0.89 | TACR1 (0.40) | TACR1MC4RMC3RMC1RMMP9 | |
| SCHEMBL6600882 | 0.88 | MMP9 (0.42) | TACR1MC4RMC3RMC1RMMP9 | |
| SCHEMBL27477312 | 0.85 | TACR1 (0.43) | TACR1MMP9MMP8 | |
| SCHEMBL6601809 | 0.85 | TACR1 (0.43) | TACR1MMP9MMP8 | |
| SCHEMBL6601553 | 0.83 | MMP9 (0.40) | TACR1MC4RMC3RMC1RMMP9 | |
| SCHEMBL6606060 | 0.81 | KLKB1 (0.39) | TACR1MMP9MMP8 | |
| SCHEMBL6602374 | 0.80 | MMP9 (0.41) | TACR1MMP9MMP8SLC6A2SLC6A4 | |
| SCHEMBL7061546 | 0.79 | MMP9 (0.40) | TACR1MMP9MMP8 | |
| SCHEMBL6601359 | 0.77 | MEN1 (0.42) | TACR1CAPN1 | |
| SCHEMBL6601229 | 0.76 | KMT2A (0.45) | TACR1CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |