Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | YAP1 | P46937 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6600255 | 0.92 | YAP1 (0.45) | KMT2AMEN1ALDH1A1YAP1MAPK1 | |
| SCHEMBL6601359 | 0.91 | MEN1 (0.42) | KMT2AMEN1ALDH1A1YAP1MAPK1 | |
| SCHEMBL6398777 | 0.91 | TACR1 (0.39) | CAPN1TACR1 | |
| SCHEMBL8910446 | 0.90 | MEN1 (0.43) | KMT2AMEN1ALDH1A1YAP1MAPK1 | |
| SCHEMBL6601362 | 0.89 | KMT2A (0.42) | KMT2AMEN1ALDH1A1YAP1MAPK1 | |
| SCHEMBL6601272 | 0.88 | MEN1 (0.42) | KMT2AMEN1ALDH1A1YAP1MAPK1 | |
| SCHEMBL6600960 | 0.88 | USP30 (0.41) | KMT2AMEN1ALDH1A1YAP1MAPT | |
| SCHEMBL6600882 | 0.86 | MMP9 (0.42) | ALDH1A1CAPN1TACR1 | |
| SCHEMBL6320628 | 0.85 | CTSS (0.52) | TACR1CTSB | |
| SCHEMBL6600504 | 0.84 | YAP1 (0.49) | KMT2AMEN1ALDH1A1YAP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | disclosed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | disclosed |
| US-6013658-A | ANIMAL GROWTH REGULATORS | NOVO NORDISK A/S (DK) | 2000-01-11 | — | — | US | disclosed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | disclosed |