Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30889068 | 0.85 | L3MBTL1 (0.42) | ACHEALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5013616 | 0.80 | MEN1 (0.43) | HTR2BACHECYP2C19LMNARAB9A | |
| SCHEMBL30889054 | 0.73 | NPC1 (0.38) | ACHECYP2C19RAB9AL3MBTL1NPC1 | |
| SCHEMBL3121433 | 0.73 | HTR2B (0.42) | HTR2BACHECYP2C19LMNARAB9A | |
| SCHEMBL17993901 | 0.72 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL28191547 | 0.72 | HTR2B (0.37) | HTR2BACHECYP2C19RAB9AMEN1 | |
| SCHEMBL29050259 | 0.70 | MMP1 (0.44) | HTR2BACHECYP2C19ENPP2LMNA | |
| SCHEMBL6570711 | 0.69 | HDAC3 (0.44) | HTR2BACHEL3MBTL1 | |
| SCHEMBL30889045 | 0.68 | ADORA3 (0.43) | CYP2C19RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL6607797 | 0.68 | ALDH1A1 (0.41) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395251-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002100818-A2 | AMINEDIOLS AS AGENTS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |