Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 8/20 | 0.57 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 8/20 | 0.57 |
| ▸ | CPN1 | P15169 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6602236 | 0.98 | GNAI3 (0.59) | GNAI3GNAO1GNAI1CPN1CPB2 | |
| SCHEMBL13655796 | 0.82 | GNAI3 (0.58) | GNAI3GNAO1GNAI1NCF1ALDH1A1 | |
| SCHEMBL1688129 | 0.81 | CYP1A2 (0.52) | CPN1CPB2SIGMAR1 | |
| SCHEMBL19203542 | 0.80 | ACHE (0.50) | GNAI3GNAO1GNAI1CPN1CPB2 | |
| SCHEMBL4678853 | 0.80 | L3MBTL3 (0.50) | GNAI3GNAO1GNAI1CPN1CPB2 | |
| Hydrochloric Acid SCHEMBL25411067 | 0.79 | CYP1A2 (0.50) | CPN1CPB2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL56070 | 0.79 | CYP1A2 (0.50) | CPN1CPB2SIGMAR1 | |
| SCHEMBL21280863 | 0.79 | HTT (0.56) | CPN1CPB2ALDH1A1 | |
| SCHEMBL5281838 | 0.78 | GNAI3 (0.62) | GNAI3GNAO1GNAI1ALDH1A1NPC1 | |
| SCHEMBL8284598 | 0.78 | ALDH1A1 (0.64) | CPN1CPB2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409479-A2 | 1-GLYCINYL-4-(1-METHYLPIPERIDIN-4-YL)PIPERAZINES AND -PIPERIDINES AS FACTOR XA ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003010160-A2 | 1-GLYCINYL-4 (METHYLPIPERIDIN-4-YL) PIPERAZINES AND -PIPERRIDINES AS FACTOR XA ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |