Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.62 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.62 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242393 | 0.83 | SMN1; SMN2 (0.51) | ALDH1A1 | |
| SCHEMBL12881322 | 0.81 | ACHE (0.51) | GNAI3GNAO1GNAI1NPC1EPHX1 | |
| SCHEMBL12881314 | 0.81 | L3MBTL3 (0.48) | GNAI3GNAO1GNAI1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27078195 | 0.81 | SMN1; SMN2 (0.50) | GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL13801429 | 0.81 | ITGB3 (0.69) | GNAI3GNAO1GNAI1ITGB3ITGA2B | |
| SCHEMBL13655796 | 0.79 | GNAI3 (0.58) | GNAI3GNAO1GNAI1NPC1ALDH1A1 | |
| SCHEMBL12881490 | 0.79 | TSHR (0.59) | GNAI3GNAO1GNAI1NPC1ALDH1A1 | |
| SCHEMBL6602806 | 0.78 | GNAI3 (0.57) | GNAI3GNAO1GNAI1NPC1ALDH1A1 | |
| SCHEMBL12881325 | 0.78 | GNAI3 (0.49) | GNAI3GNAO1GNAI1ALDH1A1CHRM2 | |
| SCHEMBL1207136 | 0.78 | GPR119 (0.56) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034444-A1 | SELECTED CGRP ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-02-10 | — | — | US | disclosed |
| EP-1863791-A1 | 2-OXO-1,2,4,5-TETRAHYDRO-1,3-BENZODIAZEPIN-3-YL-PIPERIDINES USED AS CGRP ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100026-A1 | 2-OXO-1,2,4,5-TETRAHYDRO-1,3-BENZODIAZEPIN-3-YL-PIPERIDINES USED AS CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034444-A1 | SELECTED CGRP ANTAGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | CALCRL, CALCR, CALCA | GNAI3 431/4885GNAO1 263/4885GNAI1 361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.