Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933253 | 0.89 | TACR1 (0.45) | TACR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6600367 | 0.84 | CTSS (0.56) | TACR1ALDH1A1CTSBCTSSCTSL | |
| SCHEMBL6601069 | 0.79 | SRC (0.46) | CTSBCTSSCTSLCTSKSRC | |
| SCHEMBL6600462 | 0.79 | TACR1 (0.46) | TACR1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL6600519 | 0.79 | YAP1 (0.46) | ALDH1A1MEN1KMT2APOLBNPSR1 | |
| SCHEMBL6600601 | 0.77 | GHSR (0.51) | TACR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6603855 | 0.71 | SRC (0.44) | CTSBCTSSCTSLCTSKSRC | |
| SCHEMBL6600370 | 0.70 | CTSS (0.47) | ALDH1A1MEN1KMT2APOLBCTSB | |
| SCHEMBL6600691 | 0.69 | ZAP70 (0.46) | ALDH1A1CTSBSRCZAP70 | |
| Hydrochloric Acid SCHEMBL6169748 | 0.68 | KMT2A (0.49) | TACR1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805816-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-07-28 | — | — | EP | claimed |