Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569494 | 0.83 | MEN1 (0.56) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6364172 | 0.81 | MAPT (0.41) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6606037 | 0.73 | KMT2A (0.47) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL8574923 | 0.72 | CA12 (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28958009 | 0.72 | MEN1 (0.63) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL30641227 | 0.71 | KDM4E (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL26674806 | 0.71 | KDM4E (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL6079707 | 0.71 | KDM4E (0.48) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2809797 | 0.70 | ALDH1A1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28797295 | 0.69 | KDM4E (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | disclosed |