Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607141 | 0.87 | MMP13 (0.53) | L3MBTL1FBP1TDP1GAATHRB | |
| SCHEMBL6608012 | 0.85 | LMNA (0.41) | L3MBTL1TP53ALDH1A1THRBLMNA | |
| SCHEMBL6605189 | 0.83 | MMP13 (0.60) | L3MBTL1TDP1THRBLMNAMMP13 | |
| SCHEMBL6517676 | 0.76 | MAPT (0.44) | ALDH1A1LMNAPOLB | |
| SCHEMBL6512902 | 0.75 | ALDH1A1 (0.53) | GAATP53ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6606492 | 0.75 | LMNA (0.52) | THRBLMNAMMP13 | |
| SCHEMBL6609494 | 0.74 | LMNA (0.51) | SMN1; SMN2THRBNPC1LMNAPOLB | |
| SCHEMBL16494249 | 0.73 | ACHE (0.55) | TP53ALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL6605355 | 0.73 | LMNA (0.51) | ALDH1A1SMN1; SMN2THRBNPC1LMNA | |
| SCHEMBL6517128 | 0.72 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368327-B1 | BENZO THIADIAZINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER LAMBERT CO (US) | 2004-10-20 | — | — | EP | claimed |