Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.32 |
| ▸ | FEN1 | P39748 | 5/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955656 | 0.84 | STS (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6610805 | 0.84 | CD274 (0.33) | KCNA5IDO1SLC6A2SLC6A4PDK2 | |
| SCHEMBL6605205 | 0.79 | SLC6A2 (0.36) | SLC6A2SLC6A4MEN1KMT2AALOX5AP | |
| SCHEMBL6605208 | 0.79 | SLC6A2 (0.36) | SLC6A2SLC6A4MEN1KMT2AALOX5AP | |
| SCHEMBL6214947 | 0.73 | CTSD (0.37) | KCNA5IDO1SLC6A2SLC6A4MEN1 | |
| SCHEMBL7562353 | 0.72 | CYP3A4 (0.38) | — | |
| SCHEMBL6214730 | 0.72 | EPHX1 (0.40) | MEN1KMT2A | |
| SCHEMBL6590820 | 0.72 | EPHX1 (0.40) | MEN1KMT2A | |
| SCHEMBL4763259 | 0.70 | CTSD (0.44) | SLC6A2SLC6A4MEN1KMT2ASLC6A3 | |
| SCHEMBL6589700 | 0.69 | SIGMAR1 (0.35) | KCNA5SLC6A2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307204-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-06-02 | — | — | EP | disclosed |
| EP-1307204-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |