Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6790532 | 0.75 | CYP1A2 (0.60) | ALDH1A1ADORA2ATERTCYP1A2NCF1 | |
| SCHEMBL6617731 | 0.69 | TERT (0.51) | ALDH1A1LMNAHTTADORA2ATERT | |
| SCHEMBL6606041 | 0.68 | NQO2 (0.50) | LMNAHTTADORA2ATERTKDR | |
| SCHEMBL6600579 | 0.68 | POLB (0.64) | TERTMAPT | |
| SCHEMBL6614139 | 0.68 | TERT (0.43) | ALDH1A1LMNAHTTADORA2ATERT | |
| SCHEMBL30402030 | 0.68 | ESR1 (0.40) | ALDH1A1SMN1; SMN2CYP1A2ESR1ESR2 | |
| SCHEMBL20986110 | 0.67 | LMNA (0.49) | ALDH1A1LMNASMN1; SMN2PDGFRBKDR | |
| SCHEMBL16992863 | 0.66 | ALDH1A1 (0.46) | ALDH1A1LMNAHTTSMN1; SMN2ESR1 | |
| SCHEMBL24206815 | 0.66 | CYP1A2 (0.50) | ALDH1A1LMNAHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL17687644 | 0.65 | MAPT (0.46) | ALDH1A1LMNAHTTSMN1; SMN2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373252-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002076975-A1 | CHEMICAL DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2002-10-03 | — | — | WO | disclosed |