SCHEMBL6606620

SCHEMBL6606620

CC1(Cc2c(S(C)(=O)=O)ccc(C(=O)Cl)c2Cl)N=NN=N1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
ATM Q13315 1/20 0.32
TAS2R8 Q9NYW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6603161 0.90 LMNA (0.38) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
SCHEMBL6608876 0.86 CDK1 (0.34) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
SCHEMBL28324465 0.78 MAPT (0.34) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
SCHEMBL6604522 0.77
SCHEMBL22090249 0.74 EPAS1 (0.36) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
SCHEMBL19091268 0.74 HSD17B10 (0.43) CYP1A2CYP3A4MAPTCYP2C9HPGD
SCHEMBL19091408 0.73 TAS2R8 (0.43) TAS2R8
SCHEMBL29187564 0.73 SSTR4 (0.36) HPGD
SCHEMBL9649698 0.73 ALDH1A1 (0.36) CYP1A2CYP3A4CYP2D6MAPTCYP2C9
SCHEMBL6602838 0.72 VCAM1 (0.32) CYP1A2MAPTHPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1476437-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES Bayer CropScience AG (DE) 2004-11-17 EP disclosed
WO-2003066607-A1 NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2003-08-14 WO disclosed