Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 8/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604168 | 0.95 | CRACR2A (0.42) | CRACR2ANAMPTACKR3KDM4ELMNA | |
| SCHEMBL6618083 | 0.90 | NAMPT (0.46) | CRACR2ANAMPTACKR3 | |
| SCHEMBL6618415 | 0.88 | MEN1 (0.44) | NAMPTACKR3LMNA | |
| SCHEMBL6624191 | 0.87 | CRACR2A (0.46) | CRACR2ANAMPTKDM4ELMNATDP1 | |
| SCHEMBL6617649 | 0.87 | RAB9A (0.43) | CRACR2ANAMPTACKR3KDM4ELMNA | |
| SCHEMBL6616601 | 0.87 | ACKR3 (0.48) | ACKR3KDM4ELMNA | |
| SCHEMBL6677022 | 0.86 | NAMPT (0.45) | CRACR2ANAMPTACKR3KDM4EKCNK3 | |
| SCHEMBL6614537 | 0.86 | ACKR3 (0.41) | ACKR3LMNA | |
| SCHEMBL6617757 | 0.86 | CRACR2A (0.45) | CRACR2ANAMPTKDM4ELMNATDP1 | |
| SCHEMBL6613507 | 0.86 | MAPT (0.42) | NAMPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458379-A1 | HYDROXYPHENYL-PYRAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2004-09-22 | — | — | EP | claimed |
| WO-2003051358-A1 | HYDROXYPHENYL-PYRAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA SPA (IT) | 2003-06-26 | — | — | WO | claimed |