Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188660 | 0.89 | SSTR4 (0.32) | SSTR4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5189245 | 0.89 | SSTR4 (0.32) | SSTR4HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6310051 | 0.87 | CA14 (0.36) | GAAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6302740 | 0.83 | HDAC3 (0.43) | GAAGLSHTR2CSLC6A4HDAC3 | |
| SCHEMBL7979345 | 0.83 | GAA (0.34) | GAAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7704970 | 0.82 | NOS3 (0.34) | HTR2CHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL5189850 | 0.81 | ADRA2A (0.30) | SSTR4 | |
| SCHEMBL6303033 | 0.81 | L3MBTL1 (0.37) | GAAHDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6310829 | 0.81 | RIPK1 (0.36) | HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL6302989 | 0.80 | HDAC3 (0.35) | HDAC3HDAC1HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114037-B1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN MEDICINES | SCHERING AG (DE) | 2004-05-12 | — | — | EP | disclosed |