Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449766 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL4854523 | 0.71 | — | — | |
| SCHEMBL2537847 | 0.70 | TSHR (0.30) | TSHR | |
| SCHEMBL7591793 | 0.68 | ALDH1A1 (0.35) | ALDH1A1TSHRFGFR4 | |
| SCHEMBL8060637 | 0.67 | — | — | |
| SCHEMBL8775960 | 0.67 | ALOX15 (0.32) | — | |
| SCHEMBL6267318 | 0.65 | LMNA (0.39) | ALDH1A1 | |
| SCHEMBL7592451 | 0.64 | — | — | |
| SCHEMBL3801722 | 0.63 | ALDH1A1 (0.35) | ALDH1A1TSHRFGFR4 | |
| SCHEMBL9328869 | 0.62 | ALDH1A1 (0.33) | ALDH1A1TSHRFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842927-B1 | 3-Amido-chromanylsulfonyl(thio)ureas, process for their preparation, their use and medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-02-25 | — | — | EP | claimed |
| EP-0729954-B1 | Substituted thiophene sulfonyl ureas and thioureas, process for their preparation, their use as medicaments | HOECHST AG (DE) | 2003-09-03 | — | — | EP | claimed |
| US-6506937-B2 | Used as antiarrhythmics | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-01-14 | — | — | US | claimed |
| EP-0726250-B1 | Substituted benzenesulfonylureas and -thioureas, process for their preparation and their use in the production of pharmaceutical preparations as well as pharmaceutical preparations containing them | HOECHST AG (DE) | 2000-11-02 | — | — | EP | claimed |
| EP-0779288-B1 | Substituted chromanylsulfonyl(thio)ureas, process for their preparation, their use in pharmaceutical compositions and preparations containing them | HOECHST AG (DE) | 2000-03-29 | — | — | EP | claimed |
| EP-0727416-B1 | Substituted benzenesulfonylureas and -thioureas, process for their preparation, their use as medicament or diagnostic agent, as well as medicaments containing them | HOECHST AG (DE) | 2000-01-26 | — | — | EP | claimed |
| US-5849755-A | 3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | claimed |
| US-5811448-A | PHARMACEUTICALS USEFUL FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | claimed |
| EP-0830362-A4 | PROCESS FOR THE SYNTHESIS OF VINYL SULFENIC ACID DERIVATIVES | LILLY CO ELI (US) | 1998-09-02 | — | — | EP | claimed |
| US-5792788-A | FOR TREATMENT OF CARDIAC DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-11 | — | — | US | claimed |
| EP-0830362-A1 | PROCESS FOR THE SYNTHESIS OF VINYL SULFENIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-03-25 | — | — | EP | claimed |
| US-5652268-A | TREATING CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | claimed |
| WO-1996040693-A1 | PROCESS FOR THE SYNTHESIS OF VINYL SULFENIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-12-19 | — | — | WO | claimed |
| US-5512701-A | REACTING SULFOXIDE DERIVATIVE WITH A SILYATING AGENT TO FORM SULFENATE SILYL ESTER, OPTIONALLY REACTING INTERMEDIATE WITH AN AMINE AND/OR A MERCAPTAN | ELI LILLY AND COMPANY (US) | 1996-04-30 | — | — | US | claimed |
| US-10358526-B2 | Moisture-curing polyether carbonate containing alkoxysilyl groups | COVESTRO DEUTSCHLAND AG (DE) | 2019-07-23 | — | — | US | disclosed |
| US-20170313816-A1 | MOISTURE-CURING POLYETHER CARBONATE CONTAINING ALKOXYSILYL GROUPS | COVESTRO DEUTSCHLAND AG (DE) | 2017-11-02 | — | — | US | disclosed |
| US-6506937-B2 | Used as antiarrhythmics | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-01-14 | — | — | US | disclosed |
| EP-0024292-B1 | PROCESS FOR THE SEPARATION OF URSODEOXYCHOLIC ACID FROM CHENODEOXYCHOLIC ACID AND PRODUCTS OBTAINED DURING THE PROCESS | BLASCHIM S.p.A. (IT) | 1983-06-01 | — | — | EP | disclosed |
| US-4316848-A | Process for the purification of ursodeoxycholic acid | BLASINACHIM S.P.A (IT) | 1982-02-23 | — | — | US | disclosed |
| EP-0024292-A1 | Process for the separation of ursodeoxycholic acid from chenodeoxycholic acid and products obtained during the process | BLASCHIM S.p.A. (IT) | 1981-03-04 | — | — | EP | disclosed |