SCHEMBL9328869

SCHEMBL9328869

C=CC[Si](CC=C)(CC=C)C(C(N)=O)[Si](CC=C)(CC=C)CC=C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
FGFR4 P22455 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3801722 0.63 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4
SCHEMBL7591793 0.63 ALDH1A1 (0.35) ALDH1A1TSHRFGFR4
Urea SCHEMBL28963583 0.62 ALOX15 (0.34) ALDH1A1TSHR
SCHEMBL6608637 0.62 ALDH1A1 (0.33) ALDH1A1TSHRFGFR4
SCHEMBL11361565 0.62
SCHEMBL1472599 0.62
SCHEMBL3432707 0.62
SCHEMBL174976 0.62 GRIK1 (0.50) ALDH1A1TSHRFGFR4
SCHEMBL6131545 0.62 GRIK1 (0.40) ALDH1A1TSHRFGFR4
SCHEMBL11763944 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375040-B1 Process for the preparation of retro-inverso peptides and new intermediates thereof SCLAVO SPA (IT) 1994-03-16 EP claimed
US-5116947-A PROCESS FOR THE PREPARATION OF RETRO-INVERSO PEPTIDES AND NEW INTERMEDIATES THEREOF SCLAVO S.P.A. (IT) 1992-05-26 US claimed
EP-0461407-A1 Improved process for the preparation of 2-amino(2,3,5-tri-O-benzyl-beta-D-arabinofuranosyl)adenine ASH STEVENS, INC. (US) 1991-12-18 EP claimed
EP-0375040-A2 Process for the preparation of retro-inverso peptides and new intermediates thereof SCLAVO S.p.A. (IT) 1990-06-27 EP claimed
US-5206351-A PROCESS FOR THE PREPARATION OF 2-AMINO (2,3,5-TRI-O-BENZYL-BETA-D-ARABINOFURANOSYL)ADENINE ASH STEVENS, INC. (US) 1993-04-27 US disclosed
EP-0461407-A1 Improved process for the preparation of 2-amino(2,3,5-tri-O-benzyl-beta-D-arabinofuranosyl)adenine ASH STEVENS, INC. (US) 1991-12-18 EP disclosed