Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | APOL1 | O14791 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17163848 | 1.00 | HPGDS (0.41) | HPGDSAPOL1METAP2 | |
| SCHEMBL7394465 | 0.76 | HPGDS (0.40) | HPGDSAPOL1 | |
| SCHEMBL23987187 | 0.71 | HPGDS (0.34) | HPGDSAPOL1METAP2 | |
| SCHEMBL25589899 | 0.71 | HPGDS (0.32) | HPGDS | |
| SCHEMBL26670550 | 0.70 | METAP2 (0.33) | METAP2 | |
| SCHEMBL17611616 | 0.69 | FFAR3 (0.37) | METAP2 | |
| SCHEMBL25776149 | 0.69 | FFAR3 (0.37) | METAP2 | |
| SCHEMBL14019259 | 0.67 | GAA (0.35) | HPGDS | |
| SCHEMBL318739 | 0.67 | CCR2 (0.35) | — | |
| SCHEMBL3738807 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458684-A2 | THERAPEUTIC HETEROCYCLES | AstraZeneca AB (SE) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051276-A2 | THERAPEUTIC HETEROCYCLES | ASTRAZENECA AB (SE) | 2003-06-26 | — | — | WO | disclosed |