Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6609827 | 0.75 | GPR119 (0.38) | IMPDH2IMPDH1GPR119 | |
| SCHEMBL6611560 | 0.74 | CA12 (0.42) | GPR119 | |
| SCHEMBL6611235 | 0.74 | LMNA (0.45) | IMPDH2IMPDH1GPR119 | |
| SCHEMBL3681691 | 0.73 | CA2 (0.45) | — | |
| SCHEMBL16334163 | 0.73 | KIF11 (0.42) | GPR119 | |
| SCHEMBL15225532 | 0.72 | MGLL (0.47) | — | |
| SCHEMBL6609673 | 0.72 | ESR1 (0.38) | — | |
| SCHEMBL19433226 | 0.71 | CA2 (0.42) | — | |
| SCHEMBL16432264 | 0.71 | KDM4E (0.45) | GPR119 | |
| SCHEMBL6607392 | 0.71 | ATM (0.35) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423386-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003022842-A1 | THIOPHENYLTHIOPYRANE DIOXIDES AS MMP OR TNF-ALPHA INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-20 | — | — | WO | disclosed |