Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681094 | 0.71 | ALDH1A1 (0.35) | ALDH1A1HSD17B10 | |
| SCHEMBL75106 | 0.67 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL2680065 | 0.67 | — | — | |
| SCHEMBL94930 | 0.67 | ALDH1A1 (0.55) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL96214 | 0.67 | ALDH1A1 (1.00) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL30600426 | 0.65 | ALDH1A1 (0.68) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL891486 | 0.65 | — | — | |
| SCHEMBL2680647 | 0.65 | — | — | |
| Hydrogen Sulfide SCHEMBL28185526 | 0.65 | ALDH1A1 (0.94) | ALDH1A1TDP1MEN1KMT2AHSD17B10 | |
| SCHEMBL320672 | 0.65 | ALDH1A1 (0.52) | ALDH1A1TDP1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882714-B1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS PHARMACEUTICAL CO (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-5935977-A | PHOSPHODIESTERASE IV INHIBITORS, TUMOR NECROSIS FACTOR-ALPHA PRODUCTION INHIBITORS; TREATING INFLAMMATORY AND AUTOIMMUNE DISEASES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| EP-0882714-A1 | SUBSTITUTED VINYLPYRIDINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SS Pharmaceutical Co., Ltd. (JP) | 1998-12-09 | — | — | EP | disclosed |