Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6757258 | 0.94 | ADRA1A (0.43) | ADRA1AALDH1A1KDM4EHSD17B10HPGD | |
| Trifluoroacetic Acid SCHEMBL6760834 | 0.71 | FNTA (0.53) | — | |
| SCHEMBL17009252 | 0.64 | RAB9A (0.71) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL10837292 | 0.62 | HPGD (0.59) | KDM4EHSD17B10HPGDPOLBHTT | |
| SCHEMBL27551588 | 0.62 | ADRA1D (1.00) | SMN1; SMN2ADRA1DMAPT | |
| SCHEMBL12265889 | 0.60 | HPGD (0.67) | ALDH1A1KDM4EHSD17B10HPGDRAB9A | |
| SCHEMBL31188605 | 0.60 | TAAR1 (0.55) | ALDH1A1KDM4ERAB9ASMN1; SMN2TSHR | |
| SCHEMBL4173674 | 0.60 | HPGD (0.68) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL29818326 | 0.60 | HPGD (0.68) | ALDH1A1HPGDRAB9ASMN1; SMN2POLB | |
| SCHEMBL28820363 | 0.60 | ALDH1A1 (0.60) | ALDH1A1HPGDRAB9ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395581-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, PREPARATION AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002098852-A2 | NOVEL BENZOTHIENYL OR INDOLE DERIVATIVES, AND USE THEREOF AS INHIBITORS OF PRENYL TRANSFERASE PROTEINS | PIERRE FABRE MEDICAMENT (FR) | 2002-12-12 | — | — | WO | disclosed |