Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355993 | 0.78 | L3MBTL1 (0.41) | MEN1KMT2AMAPT | |
| SCHEMBL4298346 | 0.69 | ALOX5 (0.48) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL22346875 | 0.68 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL11844598 | 0.67 | ALOX5 (0.47) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL4696046 | 0.67 | TDP1 (0.42) | ALOX5MEN1GLACYP3A4KMT2A | |
| SCHEMBL3345714 | 0.67 | CSF1R (0.31) | — | |
| SCHEMBL7020503 | 0.66 | ALOX5 (0.50) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL6871868 | 0.64 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL3413433 | 0.64 | TDP1 (0.35) | MEN1CYP3A4KMT2AMAPT | |
| SCHEMBL929896 | 0.64 | LMNA (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106345-A2 | HETEROARYL-ETHANOLAMINE DERIVATIVES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2004-12-09 | — | — | WO | disclosed |
| EP-1458719-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053971-A1 | PYRIDOQUINOXALINE ANTIVIRALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |