Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848813 | 0.81 | CA1 (0.35) | ALOX5CA1LMNAGPR55MAPT | |
| SCHEMBL7020503 | 0.80 | ALOX5 (0.50) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL11844598 | 0.77 | ALOX5 (0.47) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL12848863 | 0.77 | MEN1 (0.38) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL22924946 | 0.77 | ALOX5 (0.43) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL178515 | 0.77 | ALOX5 (0.43) | ALOX5CA1CA9NQO1MEN1 | |
| SCHEMBL21479471 | 0.75 | GPR55 (0.32) | ALOX5CA1LMNAGPR55CA2 | |
| SCHEMBL8224149 | 0.72 | L3MBTL1 (0.44) | MEN1KMT2ALMNAMAPTCYP26A1 | |
| SCHEMBL12914095 | 0.72 | POLB (0.36) | LMNAGPR55MAPTGABRA1GABRB1 | |
| SCHEMBL26710146 | 0.72 | ALOX5 (0.33) | ALOX5CA1CA9NQO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582712-B1 | Alpha-olefins polymerization catalyst | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2009-09-01 | — | — | US | claimed |
| US-20230382947-A1 | METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2023-11-30 | — | — | US | disclosed |
| US-20230167139-A1 | PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2023-06-01 | — | — | US | disclosed |
| US-11634445-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-04-25 | — | — | US | disclosed |
| US-20230043959-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE CORPORATION | 2023-02-09 | — | — | US | disclosed |
| WO-2022079127-A1 | METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT | UNIVERSITEIT GENT (BE) | 2022-04-21 | — | — | WO | disclosed |
| US-11254686-B1 | Compounds and methods for modulating adenosine A2B receptor and adenosine A2A receptor | CORVUS PHARMACEUTICALS, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| US-11178871-B2 | Herbicidal pyrimidine compounds | BASF SE (DE) | 2021-11-23 | — | — | US | disclosed |
| US-20200399257-A1 | Pesticidally Active Pyrrole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-24 | — | — | US | disclosed |
| US-20200397774-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE HOLDINGS CORPORATION | 2020-12-24 | — | — | US | disclosed |
| US-20090163592-A1 | Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORPORATION (US) | 2009-06-25 | — | — | US | disclosed |
| US-7439246-B2 | Fused heterocyclic kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
| US-20080221083-A1 | Heterobicyclic metalloprotease inhibitors | HOCHGURTEL MATTHIAS | 2008-09-11 | — | — | US | disclosed |
| US-20080221092-A1 | Heterobicyclic metalloprotease inhibitors | BLUHM HARALD | 2008-09-11 | — | — | US | disclosed |
| US-20080221083-A1 | Heterobicyclic metalloprotease inhibitors | HOCHGURTEL MATTHIAS | 2008-09-11 | — | — | US | disclosed |
| US-7410970-B2 | Substituted 1,4,-di-piperidin-4-yl-piperazine derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-08-12 | — | — | US | disclosed |
| US-7410970-B2 | Substituted 1,4,-di-piperidin-4-yl-piperazine derivatives and their use as neurokinin antagonists | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-08-12 | — | — | US | disclosed |
| US-20070142369-A1 | Combination of an H3 antagonist/inverse agonist and an appetite suppressant | SCHERING CORPORATION | 2007-06-21 | — | — | US | disclosed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | disclosed |
| US-7173031-B2 | Pyrrolotriazine kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142369-A1 | Combination of an H3 antagonist/inverse agonist and an appetite suppressant | CNR2, GPR119, GLP1R | ALOX5 2036/4885CA1 2920/4885CA9 2433/4885 |
| US-11254686-B1 | Compounds and methods for modulating adenosine A2B receptor and adenosine A2A receptor | ADORA2A, ADORA2B, ADORA3 | ALOX5 448/4885CA1 2878/4885CA9 3790/4885 |
| US-20090163592-A1 | Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | NR2E3, CRYZ, TCF12 | ALOX5 4606/4885CA1 2422/4885CA9 4260/4885 |
| US-20080221083-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, MMP3, TIMP3 | ALOX5 1243/4885CA1 325/4885CA9 267/4885 |
| US-20200397774-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | JAK1, JAK2, JAK3 | ALOX5 1792/4885CA1 4743/4885CA9 3279/4885 |
| US-20230382947-A1 | METHODS FOR PROXIMITY MEDIATED COUPLING OF A FIRST AGENT TO A SECOND AGENT | DCLRE1A, CNBP, RNGTT | ALOX5 3254/4885CA1 194/4885CA9 946/4885 |
| US-11178871-B2 | Herbicidal pyrimidine compounds | DPYD, TYMP, TYMS | ALOX5 1144/4885CA1 3265/4885CA9 3344/4885 |
| US-20230167139-A1 | PHOTOCHROMIC GERMOLE-FUSED DIARYLETHENES AND PRODUCTION THEREOF | AGL, GMNN, GAK | ALOX5 2920/4885CA1 4315/4885CA9 4454/4885 |
| US-20200399257-A1 | Pesticidally Active Pyrrole Derivatives | ACHE, DDT, CAT | ALOX5 348/4885CA1 2973/4885CA9 2222/4885 |
| US-20230043959-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | JAK1, JAK2, JAK3 | ALOX5 1971/4885CA1 4745/4885CA9 3497/4885 |
| US-20080221092-A1 | Heterobicyclic metalloprotease inhibitors | MMP13, MMP3, TIMP3 | ALOX5 1245/4885CA1 334/4885CA9 271/4885 |
| US-11634445-B2 | Organic electroluminescent materials and devices | L1CAM, EPCAM, SOD1 | ALOX5 3209/4885CA1 1023/4885CA9 695/4885 |
| US-20070032478-A1 | Kinase Inhibitors | ABL1, LCK, ERBB2 | ALOX5 4181/4885CA1 3875/4885CA9 2965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.