Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.55 |
| ▸ | CCR5 | P51681 | 9/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615174 | 0.89 | OPRL1 (0.61) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6612337 | 0.88 | LMNA (0.48) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6614708 | 0.86 | CCR5 (0.47) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6613155 | 0.85 | CCR5 (0.51) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6611611 | 0.85 | CCR5 (0.52) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6614322 | 0.85 | CCR5 (0.52) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6613998 | 0.84 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6614791 | 0.84 | OPRM1 (0.42) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6012726 | 0.83 | CXCR3 (0.59) | OPRL1OPRM1OPRD1OPRK1CCR5 | |
| SCHEMBL6611549 | 0.83 | OPRM1 (0.45) | OPRL1OPRM1OPRD1OPRK1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236726-B1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1236726-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-09-04 | — | — | EP | disclosed |