Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | KCNT1 | Q5JUK3 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6615521 | 1.00 | ADORA2A (0.40) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL6613579 | 0.81 | ADORA2A (0.47) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL6615519 | 0.76 | ALDH1A1 (0.40) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL8574398 | 0.74 | ADORA2A (0.50) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL5553184 | 0.72 | ADORA2A (0.49) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL7953446 | 0.71 | KMT2A (0.50) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL6613296 | 0.71 | ADORA2A (0.48) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL7250243 | 0.69 | ADORA2A (0.46) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL7963938 | 0.69 | ALDH1A1 (0.42) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 | |
| SCHEMBL6613269 | 0.69 | ADORA2A (0.46) | ADORA2AADORA1ALDH1A1KMT2ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794336-B2 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | AVENTIS CROP SCIENCE GMBH (DE) | 2004-09-21 | — | — | US | disclosed |
| EP-1401827-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | Bayer CropScience GmbH (DE) | 2004-03-31 | — | — | EP | disclosed |
| US-20030229125-A1 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2003-12-11 | — | — | US | disclosed |
| WO-2003000679-A2 | HERBICIDAL SUBSTITUTED PYRIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDAL AGENTS AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229125-A1 | Herbicidal substituted pyridines, their preparation, and their use as herbicides and plant growth regulators | CBR3, CBR1, CYCS | ADORA2A 3316/4885ADORA1 1577/4885ALDH1A1 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.