SCHEMBL6616072

SCHEMBL6616072

NCCCC(NC=O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.46
▸ GSR P00390 1/20 0.45
▸ CPB2 Q96IY4 4/20 0.42
▸ RNPEP Q9H4A4 1/20 0.39
▸ SLC6A5 Q9Y345 1/20 0.39
▸ MMP2 P08253 1/20 0.38
▸ MMP9 P14780 1/20 0.38
▸ GGT1 P19440 1/20 0.37
▸ CTH P32929 1/20 0.35
▸ GNPAT O15228 1/20 0.35
▸ GABRR1 P24046 2/20 0.34
▸ LMNA P02545 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27529124 1.00 FOLH1 (0.46) FOLH1GSRCPB2RNPEPSLC6A5
SCHEMBL10430391 1.00 FOLH1 (0.46) FOLH1GSRCPB2RNPEPSLC6A5
SCHEMBL1168516 0.94 GSR (0.53) FOLH1GSRCPB2RNPEPSLC6A5
SCHEMBL1168511 0.94 GSR (0.53) FOLH1GSRCPB2RNPEPSLC6A5
SCHEMBL28786641 0.94 GSR (0.53) FOLH1GSRCPB2RNPEPSLC6A5
Lysine SCHEMBL14776740 0.88 GSR (0.67) FOLH1GSRRNPEPSLC6A5MMP2
Acrylamide SCHEMBL28112667 0.85 FOLH1 (0.45) FOLH1GSRCPB2RNPEPSLC6A5
SCHEMBL13067469 0.83 FOLH1 (0.54) FOLH1GSRCPB2RNPEPSLC6A5
SCHEMBL6679962 0.82 FOLH1 (0.45) FOLH1GSRCPB2RNPEPSLC6A5
SCHEMBL8628191 0.80 ADH1B (0.46) SLC6A5CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024026072-A1 FIBROBLAST ACTIVATION PROTEIN-TARGETED COMPOSITIONS AND METHODS OF USE THEREOF RATIO THERAPEUTICS, INC. (US) 2024-02-01 — — WO disclosed
EP-3906310-A1 GENE EXPRESSION ELEMENTS AND SYSTEMS AND USE THEREOF Geneneer Ltd. (IL) 2021-11-10 — — EP disclosed
WO-2020141528-A1 GENE EXPRESSION ELEMENTS AND SYSTEMS AND USE THEREOF GENENEER LTD. (IL) 2020-07-09 — — WO disclosed
US-20160058683-A1 Hair-Straightening Compositions and Methods Cosphatech LLC 2016-03-03 — — US disclosed
EP-1427423-A1 BENZOTHIAZEPINE AND BENZOTHIADIAZEPINE DERIVATIVES WITH ILEAL BILE ACID TRANSPORT (IBAT) INHIBITORY ACTIVITY FOR THE TREATMENT HYPERLIPIDAEMIA AstraZeneca AB (SE) 2004-06-16 — — EP disclosed
WO-2003022286-A1 BENZOTHIAZEPINE AND BENZOTHIADIAZEPINE DERIVATIVES WITH ILEAL BILE ACID TRANSPORT (IBAT) INHIBITORY ACTIVITY FOR THE TREATMENT HYPERLIPIDAEMIA ASTRAZENECA AB (SE) 2003-03-20 — — WO disclosed
EP-0353752-A1 N-2, 3-butadienyl triaminoalkane derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1990-02-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160058683-A1 Hair-Straightening Compositions and Methods HOGA1, SORD, OAT FOLH1 46/4885GSR 418/4885CPB2 4838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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