Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391132 | 0.67 | TLR7 (0.39) | APLNR | |
| SCHEMBL11145787 | 0.64 | PIN1 (0.33) | PLAU | |
| SCHEMBL12476564 | 0.63 | FDPS (0.46) | — | |
| SCHEMBL29571984 | 0.62 | MEN1 (0.34) | — | |
| SCHEMBL6937537 | 0.61 | LMNA (0.33) | APLNR | |
| SCHEMBL31508111 | 0.60 | ALDH1A1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL29572684 | 0.60 | MEN1 (0.33) | — | |
| SCHEMBL2560764 | 0.60 | TRPM5 (0.44) | — | |
| SCHEMBL7533053 | 0.60 | TSHR (0.37) | — | |
| SCHEMBL25669981 | 0.60 | TLR7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490343-A1 | NEW ARYL IMIDAZOLES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS | Neurogen Corporation (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003082829-A1 | NEW ARYL IMIDAZOLES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |