Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287364 | 0.89 | ALDH1A1 (0.51) | ALDH1A1NPY5RCYP2D6GAAL3MBTL1 | |
| SCHEMBL287351 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HTTCYP2D6GAAL3MBTL1 | |
| SCHEMBL297907 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HTTGAAKDM4EMEN1 | |
| SCHEMBL660456 | 0.75 | ALDH1A1 (0.55) | ALDH1A1HTTCYP2D6L3MBTL1KDM4E | |
| SCHEMBL286776 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL287681 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HTTCYP2D6GAAKDM4E | |
| SCHEMBL287258 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL660676 | 0.69 | KMT2A (0.38) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL27854960 | 0.69 | ALDH1A1 (0.47) | ALDH1A1CYP2D6GAAKDM4EMEN1 | |
| SCHEMBL287774 | 0.67 | USP30 (0.36) | ALDH1A1NPY5RHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | claimed |
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | ALDH1A1 676/4885NPY5R 978/4885HTT 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.