Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 13/20 | 0.63 |
| ▸ | MMP13 | P45452 | 10/20 | 0.63 |
| ▸ | MMP14 | P50281 | 10/20 | 0.63 |
| ▸ | MMP2 | P08253 | 9/20 | 0.63 |
| ▸ | MMP3 | P08254 | 11/20 | 0.56 |
| ▸ | MMP8 | P22894 | 10/20 | 0.56 |
| ▸ | MMP1 | P03956 | 5/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP10 | P09238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429722 | 0.84 | MMP9 (0.72) | MMP9MMP13MMP14MMP2MMP3 | |
| SCHEMBL7429708 | 0.79 | MMP9 (0.79) | MMP9MMP13MMP14MMP2MMP3 | |
| SCHEMBL5919254 | 0.78 | MMP9 (1.00) | MMP9MMP13MMP14MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL6691931 | 0.77 | MMP3 (0.60) | MMP9MMP13MMP14MMP2MMP3 | |
| SCHEMBL7397587 | 0.77 | MMP3 (0.67) | MMP9MMP13MMP14MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL7430433 | 0.76 | MMP3 (0.56) | MMP9MMP13MMP14MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL6689267 | 0.76 | MMP3 (0.66) | MMP9MMP13MMP14MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL6691936 | 0.76 | MMP3 (0.63) | MMP9MMP13MMP14MMP2MMP3 | |
| SCHEMBL6621752 | 0.76 | MMP9 (0.62) | MMP9MMP13MMP14MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL6897571 | 0.75 | MMP13 (0.56) | MMP9MMP13MMP14MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472244-A1 | AROMATIC SULFONE HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS | Pharmacia Corporation (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045944-A1 | AROMATIC SULFONE HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-06-05 | — | — | WO | disclosed |