Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7039773 | 0.86 | NR1H3 (0.33) | — | |
| SCHEMBL6878251 | 0.77 | RAB9A (0.39) | — | |
| SCHEMBL7111182 | 0.74 | IDO1 (0.35) | — | |
| SCHEMBL6607932 | 0.72 | LMNA (0.35) | AAK1 | |
| SCHEMBL17336687 | 0.72 | LMNA (0.36) | — | |
| SCHEMBL6621925 | 0.70 | TP53 (0.36) | AAK1 | |
| SCHEMBL6880352 | 0.69 | MT-CO2 (0.46) | — | |
| SCHEMBL248463 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL6162541 | 0.69 | RECQL (0.39) | AAK1 | |
| SCHEMBL7047741 | 0.69 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379511-A1 | DIHYDRO-BENZO (b) (1, 4) DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II | F. HOFFMANN-LA ROCHE AG (CH) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083652-A1 | DIHYDRO-BENZO [b] [1, 4] DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II | F. HOFFMANN-LA ROCHE AG (CH) | 2002-10-24 | — | — | WO | disclosed |