Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10839663 | 0.78 | CYP2A6 (0.37) | — | |
| SCHEMBL11635282 | 0.74 | L3MBTL1 (0.38) | — | |
| SCHEMBL578709 | 0.72 | CYP2A6 (0.32) | — | |
| SCHEMBL7432627 | 0.71 | PARP1 (0.34) | — | |
| SCHEMBL4311977 | 0.71 | — | — | |
| SCHEMBL629844 | 0.70 | CYP1A2 (0.31) | — | |
| SCHEMBL6152174 | 0.70 | CYP1A2 (0.31) | — | |
| SCHEMBL25131 | 0.67 | ALDH1A1 (0.46) | — | |
| SCHEMBL17200851 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL535426 | 0.65 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203884-B | Passivation of homogeneous hydrogenation catalysts for the production of ethylene glycol | 伊士曼化工公司 | 2017-04-05 | — | — | CN | disclosed |
| CN-103153463-B | The method of recovery and recycle of ruthenium homogeneous catalyst | EASTMAN CHEMICAL CO. (US) | 2015-09-09 | — | — | CN | disclosed |
| US-8969632-B2 | Passivation of a homogeneous hydrogenation catalyst for the production of ethylene glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| EP-2828229-A1 | PASSIVATION OF A HOMEGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | Eastman Chemical Company (US) | 2015-01-28 | — | — | EP | disclosed |
| US-8829248-B2 | Method for recovery and recycle of ruthenium homogeneous catalysts | EASTMAN CHEMICAL COMPANY (US) | 2014-09-09 | — | — | US | disclosed |
| CN-101878188-B | Hydrogenation process for the preparation of 1, 2-diols | EASTMAN CHEM CO | 2014-07-23 | — | — | CN | disclosed |
| US-8779214-B2 | Methods for recovery and recycle of ruthenium homogenous catalysts | EASTMAN CHEMICAL COMPANY (US) | 2014-07-15 | — | — | US | disclosed |
| WO-2013142091-A1 | PASSIVATION OF A HOMEGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | EASTMAN CHEMICAL COMPANY (US) | 2013-09-26 | — | — | WO | disclosed |
| US-20130253232-A1 | METHODS FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENOUS CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2013-09-26 | — | — | US | disclosed |
| US-20130253230-A1 | PASSIVATION OF A HOMOGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | EASTMAN CHEMICAL COMPANY (US) | 2013-09-26 | — | — | US | disclosed |
| EP-0923734-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | disclosed |
| CN-1202888-A | Isoquinoline derivatives and isoquinoline combinatorial libraries | TORREY PINES INST (US) | 1998-12-23 | — | — | CN | disclosed |
| US-5840500-A | OPIOD RECEPTORS AS ANALGESICS AND CENTRALLY ACTING PAIN KILLERS | TREGA BIOSCIENCES, INC. (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | disclosed |
| WO-1998002741-A9 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | — | 1998-05-22 | — | — | WO | disclosed |
| WO-1998002741-A1 | QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-01-22 | — | — | WO | disclosed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253232-A1 | METHODS FOR RECOVERY AND RECYCLE OF RUTHENIUM HOMOGENOUS CATALYSTS | DERA, GRHPR, APEH | POLB 1053/4885 |
| US-20130253230-A1 | PASSIVATION OF A HOMOGENEOUS HYDROGENATION CATALYST FOR THE PRODUCTION OF ETHYLENE GLYCOL | HPD, TALDO1, GRHPR | POLB 735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.