Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625012 | 0.83 | CNR1 (0.46) | MAPTALDH1A1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL6625246 | 0.82 | HTT (0.49) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6624454 | 0.80 | HTT (0.42) | MAPTALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6624722 | 0.80 | HTR1A (0.47) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6623977 | 0.80 | MGAT2 (0.40) | MAPTALDH1A1SMN1; SMN2HPGDEP300 | |
| SCHEMBL6628115 | 0.80 | CNR1 (0.49) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6629709 | 0.80 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6626901 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6667869 | 0.79 | AR (0.47) | MAPTALDH1A1SMN1; SMN2TP53MEN1 | |
| SCHEMBL6628146 | 0.79 | ALDH1A1 (0.46) | MAPTALDH1A1SMN1; SMN2TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |