Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.40 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.40 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625012 | 0.88 | CNR1 (0.46) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL6625246 | 0.84 | HTT (0.49) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL6625470 | 0.83 | MAPT (0.52) | MAPTALDH1A1HSD17B10SMN1; SMN2MAPK1 | |
| SCHEMBL6625944 | 0.83 | ALDH1A1 (0.48) | MAPTALDH1A1GAAHSD17B10SMN1; SMN2 | |
| SCHEMBL6628115 | 0.82 | CNR1 (0.49) | MAPTALDH1A1SMN1; SMN2ELANEMGAT2 | |
| SCHEMBL6624722 | 0.82 | HTR1A (0.47) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL6624454 | 0.82 | HTT (0.42) | ARMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6623977 | 0.82 | MGAT2 (0.40) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL6628598 | 0.82 | MAPT (0.51) | MAPTALDH1A1ADAMTS5HTTMGAT2 | |
| SCHEMBL6668688 | 0.81 | MAPT (0.49) | MAPTALDH1A1GAAHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |