Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629709 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBKDM4EHTT | |
| SCHEMBL6626901 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTPOLBHSD17B10HTR1A | |
| SCHEMBL6625012 | 0.85 | CNR1 (0.46) | ALDH1A1MAPTRAD51PKMHTR1A | |
| SCHEMBL6628115 | 0.84 | CNR1 (0.49) | ALDH1A1MAPTRAD51KDM4EHTR1A | |
| SCHEMBL6625246 | 0.84 | HTT (0.49) | ALDH1A1MAPTRAD51PKMHTT | |
| SCHEMBL6625944 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTPKMHSD17B10KDM4E | |
| SCHEMBL6624722 | 0.80 | HTR1A (0.47) | ALDH1A1MAPTPOLBKDM4EHTR1A | |
| SCHEMBL6624454 | 0.80 | HTT (0.42) | ALDH1A1MAPTPOLBKDM4EHTR1A | |
| SCHEMBL6623977 | 0.80 | MGAT2 (0.40) | ALDH1A1MAPTKDM4EHTR1ADRD2 | |
| SCHEMBL6623561 | 0.79 | MAPT (0.40) | ALDH1A1MAPTPOLBHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |