Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2299040 | 0.86 | IDO1 (0.58) | ALDH1A1MAPTRAB9AIDO1GAA | |
| SCHEMBL6894271 | 0.81 | DPP8 (0.50) | ALDH1A1MAPTRAB9AIDO1GAA | |
| SCHEMBL11161448 | 0.80 | IDO1 (0.54) | ALDH1A1MAPTRAB9AIDO1GAA | |
| SCHEMBL11161443 | 0.80 | IDO1 (0.54) | ALDH1A1MAPTRAB9AIDO1GAA | |
| SCHEMBL5235182 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTRAB9AIDO1AKR1C3 | |
| SCHEMBL11165857 | 0.79 | IDO1 (0.53) | ALDH1A1MAPTRAB9AIDO1AKR1C3 | |
| SCHEMBL10500161 | 0.79 | DPP8 (0.58) | ALDH1A1MAPTRAB9AIDO1GAA | |
| SCHEMBL6395921 | 0.79 | IDO1 (0.53) | ALDH1A1MAPTRAB9AIDO1GAA | |
| SCHEMBL10402671 | 0.79 | IDO1 (0.53) | ALDH1A1MAPTRAB9AIDO1GAA | |
| SCHEMBL6046636 | 0.79 | RAB9A (0.59) | ALDH1A1MAPTRAB9AIDO1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812026-A | Oral carbapenem compounds containing aminosulfonyl azetidinyl | SHANDONG XUANZHU PHARM TECH CO | 2012-12-05 | — | — | CN | disclosed |
| EP-1251133-B1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-6680313-B2 | 1-HYDROXYETHYL-2(IMIDAZO(5,1B)THIAZOL-2-YL-1-CARBAPEN-2-EM-3-C CARBOXYLIC ACID OR SALT, EXCELLENT ANTIBIOTIC ACTIVITY AGAINST A WIDE SPECTRUM OF BACTERIA | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-20030027809-A1 | Novel carbapenum derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1251133-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2002-10-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030027809-A1 | Novel carbapenum derivatives | DHPS, DPEP1, OXA1L | ALDH1A1 260/4885MAPT 4740/4885RAB9A 2075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.