Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 6/20 | 0.33 |
| ▸ | CTSK | P43235 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897617 | 0.82 | KMT2A (0.33) | CA1CA2CTSSCTSKHIF1A | |
| SCHEMBL28360012 | 0.82 | PRKCA (0.36) | CA1CA2CTSKTDP1CA7 | |
| SCHEMBL30811424 | 0.80 | FOLH1 (0.41) | CA1CA2CTSSCTSKNOS1 | |
| SCHEMBL3738506 | 0.79 | DGAT1 (0.39) | CA1CA2CTSKTDP1CA7 | |
| SCHEMBL5943155 | 0.78 | CPB2 (0.39) | CA1CA2MEN1GAAKMT2A | |
| SCHEMBL3745034 | 0.78 | KMT2A (0.39) | CA1CA2CTSSCTSKTDP1 | |
| SCHEMBL3745027 | 0.78 | KMT2A (0.39) | CA1CA2CTSSCTSKTDP1 | |
| Ammonia Solution, Strong SCHEMBL27983360 | 0.77 | CA12 (0.38) | CA1CA2CTSKTDP1CA7 | |
| SCHEMBL38654786 | 0.73 | NOS1 (0.33) | CA1CA2NOS1NOS3NOS2 | |
| SCHEMBL19560807 | 0.71 | CTSK (0.48) | CA1CA2CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264836-B1 | Processes for the preparation of indolopyrrolocarbazole derivatives | BANYU PHARMA CO LTD (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-0760375-B1 | ANTITUMOR INDOLOPYPROLOCARBAZOLE DERIVATIVE | BANYU PHARMA CO LTD (JP) | 2003-11-26 | — | — | EP | disclosed |
| EP-1264836-A1 | Processes for the preparation of indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-5922860-A | Antitumor indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| US-5804564-A | Antitumor indolopyrrolocarbazole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-09-08 | — | — | US | disclosed |
| EP-0760375-A1 | ANTITUMOR INDOLOPYPROLOCARBAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |