Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626210 | 0.90 | HTR6 (0.43) | HTR6LMNAMAPTHPGDALOX15 | |
| SCHEMBL6624046 | 0.81 | HTR6 (0.57) | HTR6MAPTPTPN1 | |
| SCHEMBL6625931 | 0.75 | HTR6 (0.38) | HTR6TSHR | |
| SCHEMBL6626421 | 0.73 | HTR6 (0.39) | HTR6MAPTHPGDPTPN1 | |
| SCHEMBL6624574 | 0.70 | NOTUM (0.50) | HTR6SLC6A2 | |
| SCHEMBL6626313 | 0.70 | HTR2C (0.46) | HTR6SLC6A2 | |
| SCHEMBL6626305 | 0.70 | HTR6 (0.34) | HTR6SLC6A2 | |
| SCHEMBL10112305 | 0.70 | KDM4E (0.43) | HTR6LMNAMAPTHPGDALOX15 | |
| SCHEMBL7155151 | 0.70 | MEN1 (0.46) | LMNAHPGDCHKAPTPN1EGFR | |
| SCHEMBL1414206 | 0.70 | SIGMAR1 (0.57) | CHKASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |