Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | DRD3 | P35462 | 4/20 | 0.56 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6620732 | 0.88 | KMT2A (0.50) | DRD3ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL5242494 | 0.87 | KCNA5 (0.55) | DRD2DRD3KCNA5ALDH1A1KDM4E | |
| SCHEMBL5240284 | 0.87 | KCNA5 (0.55) | DRD2DRD3KCNA5ALDH1A1KDM4E | |
| SCHEMBL5240107 | 0.86 | KCNA5 (0.54) | DRD2DRD3KCNA5ALDH1A1KDM4E | |
| SCHEMBL5183896 | 0.86 | LDHA (0.52) | DRD2DRD3ALDH1A1KMT2AMEN1 | |
| SCHEMBL5242861 | 0.86 | KCNA5 (0.51) | DRD2DRD3KCNA5ALDH1A1KDM4E | |
| SCHEMBL6622388 | 0.85 | DRD2 (0.54) | DRD2DRD3KCNA5ALDH1A1KDM4E | |
| SCHEMBL5242627 | 0.85 | KCNA5 (0.53) | DRD2DRD3KCNA5ALDH1A1KDM4E | |
| SCHEMBL5244362 | 0.84 | KCNA5 (0.52) | DRD2DRD3KCNA5ALDH1A1KDM4E | |
| SCHEMBL5241692 | 0.84 | KCNA5 (0.52) | DRD2DRD3KCNA5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389189-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-02-18 | — | — | EP | claimed |
| WO-2002094799-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2002-11-28 | — | — | WO | claimed |