Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624933 | 0.88 | DRD2 (0.56) | KMT2AALDH1A1MEN1KDM4EF10 | |
| SCHEMBL5183896 | 0.81 | LDHA (0.52) | KMT2AALDH1A1MEN1HPGDDRD3 | |
| SCHEMBL5242857 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1MEN1SMN1; SMN2POLB | |
| SCHEMBL5904984 | 0.77 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL5240284 | 0.76 | KCNA5 (0.55) | KMT2AALDH1A1MEN1KDM4EF10 | |
| SCHEMBL5242494 | 0.76 | KCNA5 (0.55) | KMT2AALDH1A1MEN1KDM4EF10 | |
| SCHEMBL4710389 | 0.76 | HPGD (0.48) | KMT2AALDH1A1MEN1SMN1; SMN2POLB | |
| SCHEMBL5240107 | 0.76 | KCNA5 (0.54) | KMT2AALDH1A1MEN1KDM4EF10 | |
| SCHEMBL6620774 | 0.75 | SIGMAR1 (0.47) | KMT2AALDH1A1MEN1POLBTSHR | |
| SCHEMBL5183561 | 0.75 | LMNA (0.52) | KMT2AALDH1A1MEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389189-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002094799-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR LIGANDS: SUBSTITUTED 1-BENZYL-4-ARYL PIPERAZINE ANALOGUES | NEUROGEN CORPORATION (US) | 2002-11-28 | — | — | WO | disclosed |