Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626492 | 1.00 | RORC (0.45) | RORCSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL6624634 | 0.79 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6624638 | 0.79 | ALDH1A1 (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL6625925 | 0.78 | MAPT (0.46) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL6625930 | 0.78 | MAPT (0.46) | NPC1RAB9AALDH1A1MAPTNPSR1 | |
| SCHEMBL23984151 | 0.75 | KDM6B (0.47) | RORCSMN1; SMN2NPC1RAB9AMCL1 | |
| SCHEMBL1663654 | 0.74 | USP2 (0.66) | RORCSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14924002 | 0.74 | HRH3 (0.56) | RORCSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL6625140 | 0.73 | MAPT (0.56) | RAB9AALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL6628495 | 0.73 | MAPT (0.56) | RAB9AALDH1A1MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |