Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6626208 | 0.82 | ALDH1A1 (0.52) | ALDH1A1NPC1TP53HPGDNFKB1 | |
| SCHEMBL2811178 | 0.79 | PRMT1 (0.48) | ALDH1A1EGLN1PRMT1LMNAMAPT | |
| SCHEMBL13627871 | 0.78 | ALDH1A1 (0.58) | ALDH1A1NPC1TP53HPGDNFKB1 | |
| SCHEMBL9856423 | 0.77 | ALDH1A1 (0.56) | ALDH1A1NPC1TP53HPGDNFKB1 | |
| SCHEMBL17373960 | 0.76 | EGLN1 (0.48) | ALDH1A1EGLN1PRMT1LMNAMAPT | |
| SCHEMBL13270863 | 0.76 | — | — | |
| SCHEMBL161464 | 0.76 | — | — | |
| SCHEMBL29902944 | 0.75 | ALDH1A1 (0.65) | ALDH1A1NPC1TP53HPGDNFKB1 | |
| SCHEMBL2344568 | 0.75 | — | — | |
| SCHEMBL2808458 | 0.73 | PRMT1 (0.67) | ALDH1A1MAPK1SMN1; SMN2PRMT1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394148-B1 | Process for the preparation of alpha-amino acids by hydrolysis of hydantoins at elevated presssure and elevated temperature | EVONIK DEGUSSA GMBH (DE) | 2016-09-28 | — | — | EP | disclosed |
| US-9403764-B2 | Method of production of a methionine salt | EVONIK DEGUSSA GMBH (DE) | 2016-08-02 | — | — | US | disclosed |
| CN-103764240-B | Process for preparing methionine salts | EVONIK DEGUSSA GMBH (DE) | 2016-04-20 | — | — | CN | disclosed |
| US-20150175535-A1 | METHOD OF PRODUCTION OF A METHIONINE SALT | EVONIK DEGUSSA GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-9029597-B2 | Method for the conversion of methylmercaptopropionaldehyde formed from crude acrolein and crude methyl mercaptan | EVONIK DEGUSSA GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| US-9023284-B2 | Method of production of a methionine salt | EVONIK DEGUSSA GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| CN-103764240-A | Process for preparing methionine salts | EVONIK DEGUSSA GMBH | 2014-04-30 | — | — | CN | disclosed |
| CN-103764239-A | Method for the conversion of methyl mercaptopropionaldehyde produced from crude acrolein and crude methyl mercaptan | EVONIK DEGUSSA GMBH | 2014-04-30 | — | — | CN | disclosed |
| US-20130245318-A1 | METHOD FOR THE CONVERSION OF METHYLMERCAPTOPROPIONALDEHYDE FORMED FROM CRUDE ACROLEIN AND CRUDE METHYL MERCAPTAN | EVONIK DEGUSSA GMBH (DE) | 2013-09-19 | — | — | US | disclosed |
| US-20130231501-A1 | METHOD OF PRODUCTION OF A METHIONINE SALT | EVONIK DEGUSSA GMBH (DE) | 2013-09-05 | — | — | US | disclosed |
| US-6797827-B2 | Process for the preparation of alpha-amino acids by hydrolysis of hydantoins at elevated pressure and elevated temperature | DEGUSSA AG (DE) | 2004-09-28 | — | — | US | disclosed |
| EP-1394148-A1 | Process for the preparation of alpha-amino acids by hydrolysis of hydantoins at elevated presssure and elevated temperature | Degussa AG (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-20040039228-A1 | Process for the preparation of alpha-amino acids by hydrolysis of hydantoins at elevated pressure and elevated temperature | EVONIK DEGUSSA GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
| US-5990349-A | Process for the preparation of D,L-methionine or the salt thereof | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5770769-A | Process for the preparation of D,L-methionine or the salt thereof | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1998-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231501-A1 | METHOD OF PRODUCTION OF A METHIONINE SALT | MTR, MSRB3, BHMT2 | ALDH1A1 2291/4885NPC1 4093/4885TP53 4479/4885 |
| US-20130245318-A1 | METHOD FOR THE CONVERSION OF METHYLMERCAPTOPROPIONALDEHYDE FORMED FROM CRUDE ACROLEIN AND CRUDE METHYL MERCAPTAN | MAT2B, MGMT, MMAB | ALDH1A1 177/4885NPC1 4504/4885TP53 4353/4885 |
| US-20150175535-A1 | METHOD OF PRODUCTION OF A METHIONINE SALT | MTR, MSRB3, BHMT2 | ALDH1A1 2009/4885NPC1 4219/4885TP53 4518/4885 |
| US-20040039228-A1 | Process for the preparation of alpha-amino acids by hydrolysis of hydantoins at elevated pressure and elevated temperature | DAO, PEPD, HNMT | ALDH1A1 1550/4885NPC1 4047/4885TP53 2046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.