Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6628680

CCCCCCC1=C([Zr+2]C2=C(CCCCCC)C(C)=CC2)CC=C1C.[Cl-].[Cl-]

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 17/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
THRB P10828 1/20 0.33
MPEG1 Q2M385 7/20 0.32
XIAP P98170 2/20 0.32
GPR84 Q9NQS5 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
PTGES O14684 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8082447 1.00 ALOX5 (0.33) ALOX5ALDH1A1MAPTTDP1THRB
Hydrochloric Acid SCHEMBL616749 0.93
Fluoride Ion SCHEMBL3689412 0.89
Bromide SCHEMBL7184978 0.89
SCHEMBL616015 0.81 CA2 (0.32) ALOX5
SCHEMBL27463558 0.78 ALDH1A1 (0.36) ALOX5ALDH1A1MAPTTDP1THRB
Hydrochloric Acid SCHEMBL617246 0.77
Hydrochloric Acid SCHEMBL28808116 0.77 ALOX5 (0.33) ALOX5ALDH1A1MAPTTDP1THRB
SCHEMBL5343702 0.77 SCD (0.38) ALOX5ALDH1A1MAPTTDP1THRB
Hydrochloric Acid SCHEMBL4980454 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130324691-A1 Ethylene-a-Olefin Copolymer and Article SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-05 US disclosed
CN-1616496-A Catalyst component, catalyst and process for ethylenically unsaturated monomer polymerization MITSUI CHEMICALS INC (JP) 2005-05-18 CN disclosed
EP-0924223-B1 Catalyst component, catalyst and process for ethylenically unsaturated monomer polymerization MITSUI CHEMICALS INC (JP) 2004-05-19 EP disclosed
US-6444603-B1 CATALYST COMPONENT OBTAINED BY REACTING COMPOUND COMPRISING METAL OF GROUP 13 OF PERIODIC TABLE, COMPOUND CAPABLE OF BEING BONDED TO TWO OR MORE OF GROUP 13 METAL, COMPOUND CAPABLE OF FORMING IONIZING IONIC COMPOUND WITH GROUP 13 COMPOUND MITSUI CHEMICALS, INC. (JP) 2002-09-03 US disclosed
EP-0597119-B1 CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF MITSUI CHEMICALS INC (JP) 2000-12-13 EP disclosed
CN-1224026-A Catalyst component for polymerizing ethylenically unsaturated monomers, catalyst and method of use thereof MITSUI CHEMICALS INC (JP) 1999-07-28 CN disclosed
EP-0924223-A2 Catalyst component, catalyst and process for ethylenically unsaturated monomer polymerization Mitsui Chemicals, Inc. (JP) 1999-06-23 EP disclosed
US-5567777-A CONTAINING AN ALPHA-OLEFIN; TRANSPARENCY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-22 US disclosed
US-5567776-A BLEND ELASTOMERIC COPOLYMERS CONTAINING ALPHA- AND CYCLO-OLEFINS; IMPACT STRENGTH, TRANSPARENCY, FIBER OPTICS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-22 US disclosed
EP-0597119-A1 CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-05-18 EP disclosed