Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563927 | 0.82 | HSD17B10 (0.60) | MAPTALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL1688876 | 0.82 | HSD17B10 (0.60) | MAPTALDH1A1TDP1L3MBTL1HSD17B10 | |
| SCHEMBL1004343 | 0.82 | AKR1C3 (0.57) | AKR1C3MAPTGAAALDH1A1TDP1 | |
| SCHEMBL9774817 | 0.81 | AKR1C3 (0.52) | AKR1C3MAPTGAAALDH1A1TDP1 | |
| SCHEMBL7606293 | 0.79 | AKR1C3 (0.50) | AKR1C3MAPTGAAALDH1A1TDP1 | |
| SCHEMBL17179986 | 0.79 | ERN1 (0.50) | AKR1C3MAPTGAAALDH1A1TDP1 | |
| SCHEMBL2997751 | 0.77 | MAOA (0.54) | AKR1C3MAPTGAAALDH1A1TDP1 | |
| SCHEMBL3293879 | 0.77 | ALDH1A1 (0.44) | AKR1C3MAPTGAAALDH1A1TDP1 | |
| SCHEMBL7598992 | 0.77 | HSD17B10 (0.46) | ALDH1A1TDP1L3MBTL1HSD17B10KDM4E | |
| SCHEMBL21278367 | 0.77 | PLK1 (0.53) | GAAALDH1A1HSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033130-B1 | INHIBITOR OF UROKINASE PRODUCTION AND OF ANGIOGENESIS AND ITS THERAPEUTIC USE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-6365610-B1 | 1,4-EPOXY-2,3-BENZODIOXEPINS OR 1,4-EPOXY-3,2-BENZOXAZEPINES | TAIHO PHARMACEUTICAL COMPANY LTD. (JP) | 2002-04-02 | — | — | US | disclosed |
| EP-1033130-A1 | UROKINASE PRODUCTION INHIBITORS, ANGIOGENESIS INHIBITORS AND METHODS OF PREVENTION OR TREATMENT WITH BOTH | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-4477684-A | 11-Deoxy-11α-alkyl-PGE compounds from PGA compounds by lithium alkylation | THE UPJOHN COMPANY (US) | 1984-10-16 | — | — | US | disclosed |