Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299164 | 0.86 | KMT2A (0.45) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL29563927 | 0.86 | HSD17B10 (0.60) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1688876 | 0.86 | HSD17B10 (0.60) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL29953603 | 0.83 | HSD17B10 (0.56) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL6629135 | 0.77 | AKR1C3 (0.47) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL547555 | 0.72 | ALDH1A1 (0.46) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL2834703 | 0.72 | HSD17B10 (0.75) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL12942838 | 0.72 | HSD17B10 (0.46) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL548665 | 0.72 | HSD17B10 (0.50) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL3293879 | 0.72 | ALDH1A1 (0.44) | HSD17B10ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |