Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631944 | 0.79 | SSTR2 (0.43) | — | |
| SCHEMBL27828547 | 0.79 | LTA4H (0.50) | SMN1; SMN2 | |
| SCHEMBL27884428 | 0.75 | ALDH1A1 (0.44) | — | |
| SCHEMBL27731073 | 0.75 | S1PR4 (0.48) | HSPB1 | |
| SCHEMBL4660438 | 0.74 | — | — | |
| SCHEMBL17672793 | 0.73 | HSPB1 (0.51) | HSPB1 | |
| SCHEMBL6975448 | 0.73 | KCNJ1 (0.49) | — | |
| SCHEMBL6614963 | 0.73 | POLB (0.45) | SMN1; SMN2 | |
| SCHEMBL27589827 | 0.72 | CHRNB2 (0.51) | — | |
| SCHEMBL1641137 | 0.72 | LTA4H (0.61) | HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465630-A1 | CYCLIC UREA DERIVATIVES WITH 5-HT2C RECEPTOR ACTIVITY | GLAXO GROUP LIMITED (GB) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057220-A1 | CYCLIC UREA DERIVATIVES WITH 5-HT2C RECEPTOR ACTIVITY | GLAXO GROUP LIMITED (GB) | 2003-07-17 | — | — | WO | disclosed |