Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681445 | 0.85 | KMT2A (0.48) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6677140 | 0.72 | HPGD (0.47) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6633276 | 0.68 | KMT2A (0.49) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL3084657 | 0.65 | EPHB3 (0.54) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL5648630 | 0.64 | LIPE (0.47) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1720197 | 0.64 | NPC1 (0.67) | ALDH1A1KDM4CNPC1RAB9AMAPT | |
| SCHEMBL27714667 | 0.63 | KMT2A (0.57) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5647096 | 0.63 | KDM5A (0.48) | ALDH1A1KMT2AMEN1KDM5AKDM4C | |
| SCHEMBL6627826 | 0.63 | KMT2A (0.48) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6629295 | 0.63 | TP53 (0.44) | ALDH1A1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458374-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051841-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |