Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681445 | 0.82 | KMT2A (0.48) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL5650909 | 0.73 | LIPE (0.48) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL6627826 | 0.73 | KMT2A (0.48) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL1720197 | 0.66 | NPC1 (0.67) | ALDH1A1LMNAPOLBHTTMAPT | |
| SCHEMBL8832040 | 0.66 | F10 (0.81) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL5650521 | 0.66 | MEN1 (0.57) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL17079626 | 0.65 | RAB9A (0.73) | KMT2AMEN1GAAPOLBHTT | |
| SCHEMBL6037565 | 0.65 | KMT2A (0.59) | KMT2AMEN1ALDH1A1GAAPOLB | |
| SCHEMBL6632002 | 0.65 | SMN1; SMN2 (0.53) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL6457787 | 0.64 | ALDH1A1 (0.60) | ALDH1A1LMNAGAAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458374-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051841-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |