Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011335 | 0.78 | ALDH1A1 (0.52) | PNMTCD44MAOBALDH1A1MAPT | |
| SCHEMBL29789782 | 0.78 | ALDH1A1 (0.52) | PNMTCD44MAOBALDH1A1MAPT | |
| SCHEMBL5306224 | 0.76 | DRD2 (0.46) | HTR2CALDH1A1MAPTHTR2A | |
| SCHEMBL5305884 | 0.73 | ADRA2A (0.48) | HTR2CADRA2AHTR2AHTR2B | |
| SCHEMBL29674239 | 0.71 | HTR2A (0.43) | HTR2CPNMTCD44MAOBHTR2A | |
| SCHEMBL327743 | 0.71 | HTR2A (0.43) | HTR2CPNMTCD44MAOBHTR2A | |
| Hydrochloric Acid SCHEMBL1952104 | 0.69 | HTR2A (0.42) | HTR2CPNMTCD44MAOBHTR2A | |
| SCHEMBL24124810 | 0.68 | HTR2A (0.41) | HTR2CPNMTCD44MAOBHTR2A | |
| SCHEMBL5575236 | 0.68 | KDM1A (0.46) | HTR2CPNMTCD44MAOBHTR2A | |
| SCHEMBL29705936 | 0.68 | HTR2A (0.41) | HTR2CPNMTCD44MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228756-A1 | INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-11-19 | — | — | WO | disclosed |
| EP-1411881-A4 | 5HT sb 2C /sb RECEPTOR MODULATORS | ARENA PHARM INC (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-1411881-A2 | 5HT sb 2C /sb RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003086306-A2 | 5HT2C RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. (US) | 2003-10-23 | — | — | WO | disclosed |