Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5814168 | 0.97 | KCNN4 (0.56) | KCNN4MAPK1LMNACYP2D6ALDH1A1 | |
| Bromide SCHEMBL5814172 | 0.97 | KCNN4 (0.56) | KCNN4MAPK1LMNACYP2D6ALDH1A1 | |
| SCHEMBL1026821 | 0.91 | KCNN4 (0.50) | KCNN4MAPK1LMNACYP2D6ALDH1A1 | |
| SCHEMBL11621274 | 0.87 | KCNN4 (0.46) | KCNN4MAPK1LMNACYP2D6ALDH1A1 | |
| SCHEMBL18812907 | 0.85 | KIF11 (0.48) | KCNN4MAPK1LMNACYP2D6ALDH1A1 | |
| SCHEMBL11781276 | 0.80 | APP (0.48) | KCNN4MAPT | |
| SCHEMBL11768479 | 0.80 | LMNA (0.48) | KCNN4LMNACYP2D6TAAR1HDAC1 | |
| SCHEMBL26357793 | 0.80 | LTA4H (0.48) | KCNN4MAPK1LMNAALDH1A1MAPT | |
| SCHEMBL471139 | 0.80 | KCNN4 (0.48) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| Hydrochloric Acid SCHEMBL11704713 | 0.79 | APP (0.46) | KCNN4LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285769-B1 | A PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE AMINES | GENERICS UK LTD (GB) | 2014-08-13 | — | — | EP | claimed |
| US-5847216-A | Preparation of selegiline | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | claimed |
| EP-0772584-B1 | PROCESS FOR PREPARING SELEGILIN | KNOLL AG (DE) | 1998-06-17 | — | — | EP | claimed |
| EP-3538084-B1 | PHENYL AND PYRIDINYL HYDROXAMIC ACIDS | ACETYLON PHARMACEUTICALS INC (US) | 2023-11-01 | — | — | EP | disclosed |
| US-20230203030-A1 | COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS | ARVINAS OPERATIONS, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230203048-A1 | SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-06-29 | — | — | US | disclosed |
| US-20230203048-A1 | SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-06-29 | — | — | US | disclosed |
| EP-3052501-B1 | BICYCLIC ALKYNE DERIVATIVES AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2022-06-22 | — | — | EP | disclosed |
| US-20220162216-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2022-05-26 | — | — | US | disclosed |
| US-20220162217-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2022-05-26 | — | — | US | disclosed |
| US-20220010071-A1 | Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof | SK IE TECHNOLOGY CO., LTD. (KR) | 2022-01-13 | — | — | US | disclosed |
| EP-0772584-A1 | PROCESS FOR PREPARING SELEGILIN | KNOLL AKTIENGESELLSCHAFT (DE) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996008461-A1 | PROCESS FOR PREPARING SELEGILIN | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-03-21 | — | — | WO | disclosed |
| WO-1996008461-A1 | PROCESS FOR PREPARING SELEGILIN | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-03-21 | — | — | WO | disclosed |
| WO-1996004274-A1 | AZETIDINE, PYRROLIDINE AND PIPERIDINE DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 1996-02-15 | — | — | WO | disclosed |
| CN-1065453-A | Biguanide derivative, its manufacture method and the Herb of Common violet that contains this derivative | OTSUKA CHEMICAL CO LTD (JP) | 1992-10-21 | — | — | CN | disclosed |
| CN-1062544-A | The compositions of thermosetting resin that contains arylamino resin | MITSUI TOATSU CHEMICALS (JP) | 1992-07-08 | — | — | CN | disclosed |
| CN-1017055-B | Process for producing aromatic amine resin | MITSUI TOATSU CHEMICALS (JP) | 1992-06-17 | — | — | CN | disclosed |
| CN-1037721-A | Compositions of thermosetting resin | MITSUI TOATSU CHEMICALS (JP) | 1989-12-06 | — | — | CN | disclosed |
| US-4455164-A | HALOGENATED DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1984-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203048-A1 | SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, ACE2, PKD1 | KCNN4 331/4885MAPK1 767/4885LMNA 3483/4885 |
| US-20230203030-A1 | COMPOUNDS AND METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS | VHL, MDM2, XIAP | KCNN4 4871/4885MAPK1 3972/4885LMNA 3215/4885 |
| US-20220010071-A1 | Polyimide Precursor, Polyimide Precursor Composition, Polyimide Film, Method for Preparing the Same, and Use Thereof | PARG, PARN, PUF60 | KCNN4 2855/4885MAPK1 3675/4885LMNA 333/4885 |
| US-20220162216-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, ACE2, REN | KCNN4 194/4885MAPK1 877/4885LMNA 3799/4885 |
| US-20220162217-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | ACE, ACE2, REN | KCNN4 224/4885MAPK1 1173/4885LMNA 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.