Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501109 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL1421772 | 0.85 | LMNA (0.42) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL3953383 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL9392057 | 0.81 | ALDH1A1 (0.39) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL6632471 | 0.76 | ABL1 (0.46) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL5013964 | 0.76 | ABL1 (0.46) | ALDH1A1LMNAALBMAPK1ABL1 | |
| SCHEMBL24695055 | 0.75 | PYGM (0.53) | ALDH1A1LMNAALBMAPK1PYGM | |
| SCHEMBL10378942 | 0.75 | PYGM (0.53) | ALDH1A1LMNAALBMAPK1PYGM | |
| SCHEMBL4749007 | 0.75 | PYGM (0.53) | ALDH1A1LMNAALBMAPK1PYGM | |
| SCHEMBL23258398 | 0.73 | LMNA (0.43) | ALDH1A1LMNAALBMAPK1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589077-B2 | such as 5-iodo-O6-5'-cyclo-5,6-dihydro-3'-azido-3'-deoxythymidine for prophylaxis or diagnosis of viral diseases caused by hepatitis virus, herpes viruses such as Epstein-Barr virus | Kumar, Rakesh (CA) | 2009-09-15 | — | — | US | disclosed |
| US-20040242533-A1 | Antiviral nucleosides | KUMAR, RAKESH (CA) | 2004-12-02 | — | — | US | disclosed |
| EP-1208091-A1 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | GLAXO GROUP LIMITED (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001017982-A1 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | GLAXO GROUP LIMITED (GB) | 2001-03-15 | — | — | WO | disclosed |
| EP-0614357-A1 | IMMUNOPOTENTIATORY AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-09-14 | — | — | EP | disclosed |
| WO-1994007479-A2 | IMMUNOPOTENTIATORY AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242533-A1 | Antiviral nucleosides | ENTPD5, DUT, ADA | ALDH1A1 1901/4885LMNA 2597/4885ALB 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.