SCHEMBL1421772

SCHEMBL1421772

Cc1cn([C@H]2CC[C@@H](CO)O2)c(=O)n(F)c1=O

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.42
ALB P02768 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
ABL1 P00519 1/20 0.38
RIN1 Q13671 1/20 0.38
CYP1A2 P05177 1/20 0.36
TSHR P16473 2/20 0.34
TK1 P04183 1/20 0.34
PKM P14618 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4501110 0.85 ALDH1A1 (0.41) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL4501109 0.85 ALDH1A1 (0.41) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL23258398 0.85 LMNA (0.43) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL5638638 0.84 LMNA (0.42) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL9545096 0.84 LMNA (0.42) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL9392057 0.82 ALDH1A1 (0.39) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL14154578 0.82 LMNA (0.39) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL3953383 0.82 ALDH1A1 (0.39) LMNAALBALDH1A1MAPK1ABL1
SCHEMBL7595956 0.82
SCHEMBL2873282 0.78 LMNA (0.52) LMNACYP1A2TSHRTK1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112672764-A Conjugates 格莱科斯生物医药公司 2021-04-16 CN claimed
US-9198893-B2 Combination antitumor therapy GALERA LABS, LLC (US) 2015-12-01 US claimed
US-20110136756-A1 COMBINATION ANTITUMOR THERAPY BIOSSIL INC. (CA) 2011-06-09 US claimed
EP-2296645-A2 COMBINATION ANTITUMOR THERAPY Kereos, Inc. (US) 2011-03-23 EP claimed
WO-2009143454-A2 COMBINATION ANTITUMOR THERAPY KEREOS, INC. (US) 2009-11-26 WO claimed
EP-1495325-B1 USE OF NUCLOEOSIDE DERIVATIVES COMPRISING A CITRATE GROUP FOR PRODUCING ANTIBODIES HAVING AFFINITY FOR TRIPHOSPHORYLATED NUCLEOSIDES AND USES THEREOF CENTRE NAT RECH SCIENT (FR) 2009-05-13 EP claimed
EP-1485395-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS Biota, Inc. (US) 2004-12-15 EP claimed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 WO claimed
EP-1194168-A2 METHODS AND PRODUCTS FOR MANIPULATING UNCOUPLING PROTEIN EXPRESSION UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2002-04-10 EP claimed
WO-2000078941-A2 METHODS AND PRODUCTS FOR MANIPULATING UNCOUPLING PROTEIN EXPRESSION UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2000-12-28 WO claimed
EP-4746875-A2 CARCINOGENESIS REDUCTION WITH PENTAAZA MACROCYCLIC RING COMPLEX Galera Labs, LLC (US) 2026-05-27 EP disclosed
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX GALERA LABS LLC (US) 2026-05-21 US disclosed
US-20260108480-A1 METHODS FOR INDUCING PROLIFERATION OF STEM CELLS UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2026-04-23 US disclosed
EP-3921420-B1 DRUG DELIVERY COMPOSITIONS FOR OCULAR ADMINISTRATION OF THERAPEUTICS AND METHODS OF USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-04-08 EP disclosed
US-20260069541-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF ACTIVE AGENTS INCLUDING NUCLEIC ACIDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 US disclosed
US-5449664-A Nucleosides SYNTEX (U.S.A.) INC. (US) 1995-09-12 US disclosed
WO-1992017485-A1 PREPARATION OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES AND 2'-DEOXYNUCLEOSIDES FROM ACYCLIC, ACHIRAL PRECURSORS EMORY UNIVERSITY (US) 1992-10-15 WO disclosed
EP-0482081-A1 ANTIVIRAL COMPOSITION. HARMENBERG JOHAN (SE) 1992-04-29 EP disclosed
WO-1991001137-A1 ANTIVIRAL COMPOSITION HARMENBERG JOHAN (SE) 1991-02-07 WO disclosed
EP-0332626-A1 COMPOSITIONS FOR TREATING VIRAL INFECTIONS IN HUMANS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1989-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108480-A1 METHODS FOR INDUCING PROLIFERATION OF STEM CELLS CYP4X1, SLC6A7, ZFX LMNA 3499/4885ALB 4828/4885ALDH1A1 503/4885
US-20260069541-A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF ACTIVE AGENTS INCLUDING NUCLEIC ACIDS PHAX, RNMT, PRKCZ LMNA 630/4885ALB 4356/4885ALDH1A1 4778/4885
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX CD274, PDCD1, PDCD1LG2 LMNA 3759/4885ALB 497/4885ALDH1A1 2841/4885
US-20110136756-A1 COMBINATION ANTITUMOR THERAPY SOD3, SOD1, MCL1 LMNA 3699/4885ALB 3527/4885ALDH1A1 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.