Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631235 | 0.84 | RORC (0.43) | MAPTALDH1A1SCN4AMEN1KMT2A | |
| SCHEMBL6635974 | 0.81 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL6632002 | 0.81 | SMN1; SMN2 (0.53) | AURKAALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5650068 | 0.77 | ALDH1A1 (0.55) | MAPTALDH1A1SCN4AMEN1KMT2A | |
| SCHEMBL6630359 | 0.75 | ALDH1A1 (0.49) | ALDH1A1SCN4AMEN1KMT2ARAB9A | |
| SCHEMBL6629379 | 0.74 | NPC1 (0.46) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL5651163 | 0.73 | SCN4A (0.47) | MAPTALDH1A1SCN4AMEN1KMT2A | |
| SCHEMBL6634859 | 0.73 | RAB9A (0.41) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL5648908 | 0.73 | ALDH1A1 (0.55) | MAPTALDH1A1ACHE | |
| SCHEMBL6631787 | 0.72 | KMT2A (0.42) | MAPTALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |